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Flashcards on Skeletal Muscle Metabolism
Click on the flashcard to see the answer
What is the primary energy source for muscle contraction?
Adenosine triphosphate (ATP)
Which biochemical source for producing ATP is used first?
Creatine phosphate
How long can creatine phosphate supply energy to a working muscle?
8-10 seconds
What is the byproduct of ATP production from glycogen without using oxygen?
Lactic acid
Which system produces ATP for endurance events?
Aerobic respiration
What are the proteins involved in muscle filaments and sarcomeres?
Actin, tropomyosin, troponin, myosin
What triggers muscle contraction at the molecular level?
Release of acetylcholine (Ach) neurotransmitter
What happens to tropomyosin when Ca2+ binds to troponin?
Tropomyosin moves, exposing myosin-binding sites on actin
What causes muscle fatigue?
Lack of ATP, low oxygen, and accumulation of lactic acid
Which genetic deficiency results in muscle weakness due to muscle glycogen accumulation?
Pompe disease
What is the primary cause of Duchenne muscular dystrophy?
Altered dystrophin gene
What is the main function of mitochondria in muscle cells?
Producing ATP through oxidative phosphorylation
Which autoimmune disorder affects neuromuscular signaling at the motor endplate?
Myasthenia gravis
In which disease does immune cell destruction of nerve sheath myelin cause paralysis of skeletal muscles?
Multiple sclerosis
What type of questions are answered by studying skeletal muscle metabolism?
How does the body generate energy for muscle contractions?
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Test Your Knowledge
What is the primary energy source for muscle contraction?
Adenosine triphosphate (ATP)
Creatine phosphate
Glycogen
Glucose
Check Answers
Which system produces ATP for endurance events?
Creatine phosphate
Glycogen
Aerobic respiration
Anaerobic respiration
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What is the byproduct of ATP production from glycogen without using oxygen?
Glucose
Lactic acid
Pyruvate
Carbon dioxide
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What triggers muscle contraction at the molecular level?
Release of acetylcholine (Ach) neurotransmitter
Depolarization of the muscle membrane
Activation of motor neurons
Increase in calcium levels
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Which genetic deficiency results in muscle weakness due to muscle glycogen accumulation?
Duchenne muscular dystrophy
Pompe disease
Becker muscular dystrophy
Myasthenia gravis
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What is the main function of mitochondria in muscle cells?
Storing calcium ions
Producing glycogen
Producing ATP through oxidative phosphorylation
Contracting muscle fibers
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Which autoimmune disorder affects neuromuscular signaling at the motor endplate?
Multiple sclerosis
Rheumatoid arthritis
Myasthenia gravis
Muscular dystrophy
Check Answers
What type of questions are answered by studying skeletal muscle metabolism?
How does the body generate energy for muscle contractions?
How does muscle growth occur?
What is the role of calcium in muscle contraction?
How does exercise affect muscle strength?
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What causes muscle fatigue?
High levels of ATP
Increased oxygen availability
Lack of ATP, low oxygen, and accumulation of lactic acid
Lowered calcium levels
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What is the primary cause of Duchenne muscular dystrophy?
Acetylcholine receptor autoantibodies
Altered dystrophin gene
Mutations in mitochondrial tRNA genes
Deposition of immune complex in joints
Check Answers
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